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These tails are subject to a number of put up-translational covalent modifications, together with acetylation, phosphorylation, ubiquitination, sumoylation and methylation (reviewed in 1 ).

Your price range can't sustain it. The exception to the rule is the DOT1 household, members of which methylate K79 in the globular region of histone H3 and which are structurally not associated to SET-domain proteins four - 6 Recent work means that SET-area-containing proteins methylate just a few proteins along with histones (see later)